Aboubakr Mohamed Elnashar
Benha university Hospital , Egypt
Title: Role of chronic endometritis in Repeated miscarriage and repeated implantation failure
Biography
Biography: Aboubakr Mohamed Elnashar
Abstract
Recently, there has been an increasing interest in the role of CE in RM and RIF. One of the etiologies may be CE. Limited publications exist regarding evaluation and treatment for CE in RM and RIF. The impact of CE on reproductive capacity is controversial. CE is a persistent inflammation of the endometrium that is characterized by the presence of plasma cells. Prevalence of CE is highly variable in the scientific literature depending on various techniques used for diagnosis. (in RIF: 30.3% to 66%; in RM: 42.9% to 56%.). Various reports suggest an infectious etiology of CE. CE is usually asymptomatic. Different methods for diagnosis: culture, hysteroscopy, and histology specimens. Histologic diagnosis (H & E staining) is the gold standard for the diagnosis of CE. Immunohistochemistry is more accurate diagnostic method. Regimen for treatment: Ofloxacin: 400 mg daily or Doxycycline: 100 mg twice daily for 2 weeks. If persistent CE: Ciprofloxacin: 500mg and Metronidazole: 500 mg twice daily for 2 weeks. After treatment with antibiotics, LBR among women with RPL and CE is similar to women without CE