Muhamed Bakry
KFS General Hospital, Egypt
Title: Cytomegalovirus, Parvovirus B19, Varicella Zoster, and Toxoplasmosis in Pregnancy
Biography
Biography: Muhamed Bakry
Abstract
Among the many physiologic changes that occur during pregnancy, the maternal immune system is altered to dampenthe maternal inflammatory response and allow for fetal antigen tolerance (1, 2). Although such immunologic changesdiminish the chance of fetal rejection, they potentially increase maternal and fetal vulnerability to certain infectiousdiseases. Common infections that cause mild-to-moderate disease in healthy adults and children can cause serious maternal and fetal complications if acquired during pregnancy. A unique concern with maternal infection is the potential for mother-to-child transmission or congenital infection. Cytomegalovirus (CMV), parvovirus B19, varicellazoster virus (VZV), and toxoplasmosis are common infections associated with moderate-to-severe fetal and infant complicationswhen acquired congenitally. The purpose of this document is to update the current understanding of these infections, including their clinical presentations; their modes and risks of perinatal transmission; and their maternal,fetal, and infant effects, and to offer guidelines for preventing and managing these infections during pregnancy